Limb loss is one of the deadliest complications of diabetes, chronic kidney disease, and peripheral arterial disease.
Diabetes, chronic kidney disease, and peripheral arterial disease are associated with microvascular dysfunction, leading to foot ulcerations and amputations. These complications pose a considerable cost burden to health care systems around the world. A foot ulcer precedes 85% of amputations (Edmonds et al., 2021), but they are preventable with early identification, timely referral to specialists, and targeted intervention. One pervasive challenge for clinicians is that there is no easy to use and readily available technology to help them risk-stratify and identify these patients.