Spatial frequency domain imaging
Spatial frequency domain imaging (SFDI) is the heart of our technology platform and the next generation in optical imaging. Invented by Modulim’s founder and CTO David Cuccia, Ph.D., and his colleagues at UC Irvine’s Beckman Laser Institute, SFDI provides accurate quantitative measurement of tissue oxygen availability, extraction, and saturation in tissue by incorporating the following patented proprietary processes:
- Multispectral imaging: Multiple wavelengths of visible and near-infrared light. This broad spectrum of light provides clinically relevant surface (0-1mm deep) and subsurface (1-3mm deep) tissue contrast over large areas.
- Structured illumination: A proprietary technique based on years of research that allows us to calculate tissue scattering and ensures accurate, repeatable measurements of hemoglobin across different tissue types.
- Predictive algorithms: Ongoing development to translate SFDI outputs for clinical decision support.
By using all three in concert, we can better guide clinicians in doing what they need to do for their patients.